Kasper D. Rand

Kasper obtained a Master of Science in Biochemistry at University of Copenhagen in 2004. He then joined Novo Nordisk Inc. as a research scientist and obtained an industrial Ph.D. degree from the University of Southern Denmark in 2007 through his work on characterizing the structure of therapeutic proteins by hydrogen exchange and mass spectrometry. After a brief period as a research consultant at Novo Nordisk, he joined the Protein Research Group at the University of Southern Denmark as a PostDoc, where he worked with Prof. O.Jensen and Prof. T. Jørgensen. During this period, he developed a mass spectrometry method (HX-ETD) capable of measuring the hydrogen exchange of individual residues in a protein. In 2008, he obtained a fellowship from the Danish Research Council and joined the group of Prof. J. Engen at Northeastern University in Boston as a visiting fellow. Here he introduced a method for analysis of proteins by rapid gas-phase hydrogen exchange and went on to work with Prof. E. Reinherz and Prof. M. Eck and at the Dana-Farber Cancer Institute of Harvard Medical School on characterizing proteins and protein complexes critical for HIV infection and cancer. In 2010, he joined the group of O.Michielin as a visiting fellow of the Human Frontier Science Program where he is working on improving structural prediction of protein-protein complexes by use of experimental constraints from hydrogen exchange measurements.